MK 677 is an orally administered growth hormone secretagogue that is designed to stimulate the pituitary gland to release growth hormone. It was originally formulated to manage health problems like osteoporosis, obesity and muscle wasting, but MK 677 has been shown to promote an increase in lean body mass as well as a boost in IGF-1 serum concentration during clinical runs. For this reason, it didn’t take people in the bodybuilding industry very long to start using it as a way to enhance their performance.
Ostarine, also known as MK-2866 is a SARM (selective androgen receptor module) created by GTx to avoid and treat muscle wasting. It can, later on, be a cure for avoiding atrophy (total wasting away of a body part), cachexia, sarcopenia and Hormone or Testosterone Replacement Therapy. This type of SARM cannot only retain lean body mass but as well as increase it. Ostarine is often mistaken as S1 but S1 was created earlier and is no longer going through more expansion.
S-4 is by far the most versatile SARM ever created. Not only is it the first SARM approved for a stage 2 research study, it has become the most analyzed and investigated SARM so far. After the discovery of its anabolic potential, the primary purpose of S-4 aimed to develop an alternative treatment to age-related muscle wasting, osteoporosis, and similar symptoms of hypogonadism, or end-stage renal disease.
GW 501516 (or Cardarine), is a research chemical developed in the 1990s to prevent and cure tumor formation in the colon, prostate, and breasts. Studies done in the early 2000s have found that GW 501516 and other PPAR agonists have also been able to stop metabolic disorders such as obesity and diabetes through specific gene expressions.
LGD-4033, known also as Ligandrol and Anabolicum, is the strongest orally bioavailable, non-steroidal, selective androgen receptor modulator (SARM) currently on the market. Popular with athletes, power lifters and body builders for its ability to both bulk and cut, Ligandrol produces steroid-like results without the side effects.
Research has shown that RAD-140 acts on selective androgen receptors exclusively in muscle and bone tissues therefore it mimics hormone receptors. Research has shown rapid increase in building muscular tissues and also research has shown RAD-140 shows strong increases in stamina and endurance during high intensity exercise to go along with great increases in muscle recovery.
SR9009, also known as Stenabolic, is a selective androgen receptor modulator (SARM) that has been referred to as ‘exercise in a bottle’. Initial trials on mice showed an increase in muscle and metabolic rate without exercise, and enhanced stamina with exercise. Essentially, SR9009 has shown promise to improve endurance and metabolism to become leaner.
YK11, also known as Myostine, is considered one of the strongest SARMs on the market. In fact, it’s so strong and has comparable anabolic activity to steroids that it may actually be a synthetic steroid that was mislabeled a SARM in the first place.